Establishes a Countering Unmanned Aircraft Systems Coordinator to oversee Department of Homeland Security efforts on addressing threats from unmanned aircraft systems.

Authorizes Swedish Match Inc. to market eight smokeless tobacco products in the US using modified warning labels and advertisements that indicate reduced health risks in comparison to regular cigarettes.

Reauthorizes the Stem Cell Therapeutics and Research Act of 2005.

Extends compensation and eligibility rules for spouses of veterans who died from ALS.

Modifies required warning labels for cigarette packages and advertisements to better reflect known health risks and mandates that new textual warnings be printed alongside color images visualizing the negative health consequences.

Proposes significant new use rules (SNUR) for 31 chemical substances, including multiwalled carbon nanotubes (generic), and includes guidelines to minimize risk of harmful exposure to humans and the environment.

Imposes an excise tax on manufacturers, producers, and importers of opioids, the revenue from which would be allocated to programs supporting opioid abuse prevention and addiction treatment.

Requires that executive branch agencies treat guidance documents as non-binding both in law and in practice, take public input into account when appropriate in formulating guidance documents, and make guidance documents readily available to the public.

Recommends steps clinicians can take to safely reduce or discontinue their patients' use of prescription opioid drugs, especially after long-term use.

Provides clinicians with guidance on best practices for reducing the dosage or discontinuing the use of opioids among long-term pain management patients.

Establishes a tobacco product standard that limits the concentration of nicotine in e-liquids to less than 20 milligrams per milliliter.

Rejects (without prejudice) bid by Tri-State Generation and Transmission to qualify for federal, rather than state, regulation to avoid Colorado requirements that electric power providers move to 100% renewable power by 2040.