The National Institutes of Health (NIH) has issued a Request for Information inviting comments and suggestions to be considered during the development of a challenge prize for Alzheimer's disease research.
Section 2002 "Eureka Prize Competitions" of the 21st Century Cures Act, enacted on December 13, 2016, requires NIH to support and report on prize competitions in areas of biomedical science that could: 1) realize significant advancements and 2) improve health outcomes in human diseases and conditions that have a disproportionately small research investment relative to expenses for prevention and treatment, represent a serious and significant disease burden, or for which there is potential for significant return on investment.
Ideas may be submitted in any area of Alzheimer's disease (AD) or related dementias (ADRD) research, and interested parties may wish to consider the full set of AD/ADRD research implementation milestones as a source for priorities identified by the research community. In addition, the International Alzheimer’s Disease Research Portfolio (IADRP) also offers insights into progress made in funding particular disease areas, and potential gaps for future focus.
Individuals wishing to comment may consider providing feedback on the following (either on the ideas below, or any other idea that a commentator would like to suggest):
- Clarity of the goal and fit with a prize model (as opposed to a grant or other mechanism)
- Duplication with other ongoing activities
- Attractiveness of the question to a broad audience of possible solvers
- Time needed to develop a prize submission and for judges to identify a winner
- Metrics that judges might use to identify a winner
- Minimal dollar amount for the award, that would make the prize attractive to solvers
- Methodology for measuring the effect of the prize goal on Federal expenditures
Ideas that are amenable to small business approaches are also welcome.
More information is available via the NIH's website.